Should I put all my information in one family file or should I create multiple family files?
There is no right or wrong answer to this question. Each approach has advantages and disadvantages.
For most people, having one family file will suffice, however, the decision that's right for you will largely depend on the type of research you plan to do.
For a discussion of this topic, check out Jan McClintock's article How Many Family Files?
For more discussion, click the Manual button and search for multiple family files.